ENHANCED THERAPEUTIC EFFICACY OF DOXORUBICIN AGAINST MULTIDRUG-RESISTANT BREAST CANCER WITH REDUCED CARDIOTOXICITY

Enhanced therapeutic efficacy of doxorubicin against multidrug-resistant breast cancer with reduced cardiotoxicity

AbstractDoxorubicin (DOX), a commonly used anti-cancer drug, is limited by its cardiotoxicity and multidrug resistance (MDR) of tumor cells.Epigallocatechin gallate (EGCG), a natural antioxidant component, can effectively reduce the cardiotoxicity of DOX.Meanwhile, EGCG can inhibit the expression of P-glycoprotein (P-gp) and reverse the MDR of tumo

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Determination of the relatedness, ease of hybridization and gene exchange among members of the genus Capsicum in Nigeria

The fruit of Capsicum plants have a variety of names depending on place and type.This research was focused Driftwood at studying the exchange of genes amongst members of the genus Capsicum in Nigeria.The process of interspecific and intervarietal hybridization of two (2) species of the genus Capsicum; C.annuum and C.frutasense were carried out and

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A pilot randomized controlled trial comparing the efficacy of exercise, spinal manipulation, and neuro emotional technique for the treatment of pregnancy-related low back pain

Abstract Background This pilot randomized controlled trial evaluated the feasibility of conducting a full scale study and compared the efficacy of exercise, spinal manipulation, and a mind-body therapy called Neuro Emotional Technique for the treatment of pregnancy-related low back pain, a common morbidity of pregnancy.Methods Healthy pregnant wome

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